Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.
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Updated on Mar 4, 2014

Interactive Scores (IScores) applies genotypic scores to distinct HIV-1 RT and protease mutation patterns from ~40,000 individuals with group M sequences.
  • 'Show All Patterns & Levels': The complete list of all patterns and resistance levels (1 to 5).
  • 'Show Specific Patterns': The complete list of all patterns and resistance levels containing a specific mutation or mutation combination.

  • 'Score Changes' text box: To examine the effects of a score change enter changes in the following format (e.g. 'ABC:30, TDF:30').
  • 'Include' checkbox: Uncheck to assign all scores to 0.
  • 'Maximum Result Count': Limits the number of mutation patterns returned: It takes ~5 seconds to return 100 recalculated resistance levels.
INI Scores (HIVdb 7)
Algorithm           
      Maximum Result Count
IncludeMutationRALEVGDTGScore Changes
51Y151510
66I15600
66A15600
66K606010
68V000
74M10105
92Q306010
92V30605
92G15305
95K10100
97A15105
114Y000
118R303010
121Y30305
128T000
138K151510
138A151510
138D000
140S303010
140A303010
140C303010
143C60100
143R60100
143H60100
IncludeMutationRALEVGDTGScore Changes
143K60100
143S60100
143G60100
143A60100
145S0600
146P0600
147G0600
148H606020
148K606020
148R606020
151I000
151A15300
151L306015
153Y01510
153F01010
155H606010
155S30300
155T30300
157Q15150
163R15150
163K15150
230R15150
263K153015
143CRSGA+163R050
143CRSGA+230R050
IncludeMutationRALEVGDTGScore Changes
143CRSGA+74MI050
143CRSGA+97A050
148HRK+138AK0025
148HRK+140SAC0025
148HRK+163RK005
148HRK+74M005
148HRK+97A005