HIV Drug Resistance Summaries
Notes on Resistance Mutations; including extensive relevant references for NNRTI, PI, and INI
Listing of comments and scores (sortable) for individual mutations and combination of mutations. These comments and scores are those used in the HIVdb interpretation reports.
IScores (Interactive Scores) displays the complete set of interpretations for about 50,000 well-characterized RT and PR population-based plasma group M sequences. The default interpretation system is HIVDB v6.2 but we are looking forward to adding other systems. IScores shows the frequency with which every mutation pattern occurs and allows users to observe the effect that changes to mutation rules or scores will have on the susceptibility to each ARV in an ARV class.
Summary of the key mutations associated with each antiretroviral drug. Indications for drug use in first-line, second-line, and salvage therapy regimens.