HIV Drug Resistance Database

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HIV Treatment Websites

Clinical Guidelines and Drug Information
Antiretroviral Drug Prescribing Information
Educational and CME Sites
Biomedical Journals
HIV-Related Scientific Meetings and Conferences
HIV/AIDS Research Databases
Clinical Trials
Telephone Consultation Services

Last updated: 05/09/12

Clinical Guidelines and Drug Information

Site/URL	Description
DHHS: AIDSinfo Clinical Guidelines	Guidelines from the Department of Health and Human Services, including: Adult/adolescent Pediatric Perinatal Post-exposure prophylaxis Opportunistic infections Testing
AIDSinfo Drug Database	Choose an FDA-approved or investigational anti-HIV drug and find links to guideline tables and drug records.
CDC Guidelines	Includes CDC guidelines for community planning, counseling and testing, evaluation, occupational and non-occupational post-exposure prophylaxis, patient care, prevention, surveillance, and treatment.
CDC recommendations for HIV testing	2006 recommendations for testing of adults, adolescents, and pregnant women.
WHO HIV/AIDS Guidelines	World Health Organization guidelines including post-exposure prophylaxis, prevention of mother-to-child transmission, surveillance and public health recommendations, TB-HIV co-management, and the UNAIDS/WHO AIDS Epidemic Update.
IAPAC Drug Guide 2007	Clear, concise summaries of all FDA-approved drugs, including visuals.
HIV Drug Interactions	Check for drug interactions and pharmacology resources. Developed and maintained by the University of Liverpool.
PDR.net	Comprehensive drug information including the full text of package inserts. Downloadable drug interactions to PDA available. Registration required (free).
HIV Drug Resistance Program	Managed by National Institute of Standards and Technology
BHIVA Guidelines	British HIV Association guidelines including management of HIV infection in pregnant women, immunization and treatment, HIV associated malignancies, and HBV-HIV, HCV-HIV, and TB-HIV co-infection.
Medical Management of HIV Infection	Manual of diagnosis and treatment by Drs. John G. Bartlett and Joel E. Gallant, Johns Hopkins University. Requires log-in (free).
IDSA Practice Guidelines for the Treatment of Tuberculosis	Infectious Disease Society of America guidelines, published 2003.

Drug Prescribing Information

Drug Name(s)/Abbreviation	Trade Name(s)	Manufacturer	Documents
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
abacavir (ABC)	Ziagen®	Glaxo SmithKline	Prescribing Information Microbiology Reviews Medical Reviews
didanosine (DDI)	Videx/Videx EC®	Bristol-Myers Squibb	Prescribing Information Microbiology Reviews Medical Reviews
emtricitabine (FTC)	Emtriva®	Gilead	Prescribing Information Microbiology Reviews Medical Reviews
lamivudine (3TC)	Epivir®	GlaxoSmithKline	Prescribing Information Medical Reviews
stavudine (D4T)	Zerit®/Zerit XR®	Bristol-Myers Squibb	Prescribing Information Microbiology Reviews Medical Reviews
tenofovir (TDF)	Viread®	Gilead	Prescribing Information Microbiology Reviews Medical Reviews
zidovudine (AZT, ZDV)	Retrovir®	GlaxoSmithKline	Prescribing Information Medical Reviews
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
efavirenz (EFV)	Sustiva®	Bristol-Myers Squibb	Prescribing Information Microbiology Reviews Medical Reviews
etravirine (ETV)	Intelence®	Tibotec	Prescribing Information Microbiology Reviews Medical Reviews
nevirapine (NVP)	Viramune®	Boehringer Ingelheim	Prescribing Information Microbiology Reviews Medical Reviews
rilpivirine (RPV)	Edurant®	Johnson and Johnson/Tibotec	Prescribing Information Microbiology Reviews Medical Reviews
Protease Inhibitors (PIs)
amprenavir (APV)-discontinued	Agenerase®	Glaxo SmithKline	Prescribing Information Microbiology Reviews Medical Reviews
atazanavir (ATV)	Reyataz®	Bristol-Myers Squibb	Prescribing Information Microbiology Reviews Medical Reviews
darunavir (DRV)	Prezista®	Tibotec	Prescribing Information Microbiology Reviews Medical Reviews
lopinavir and ritonavir (LPV/r)	Kaletra®	Abbott	Prescribing Information Microbiology Reviews Medical Reviews
fosamprenavir (FPV)	Lexiva®	Glaxo SmithKline	Prescribing Information Microbiology Reviews Medical Reviews
indinavir (IDV)	Crixivan®	Merck	Prescribing Information
nelfinavir (NFV)	Viracept®	Pfizer	Prescribing Information Microbiology Reviews Medical Reviews
ritonavir (RTV)	Norvir®	Abbott	Prescribing Information Medical Reviews
saquinavir (SQV)	Invirase®	Roche	Prescribing Information Microbiology Reviews Medical Reviews
tipranavir (TPV)	Aptivus®	Boehringer Ingelheim	Prescribing Information Microbiology Reviews Medical Reviews
Fusion Inhibitors
enfurvirtide (ENF, T-20)	Fuzeon®	Roche	Prescribing Information Microbiology Reviews Medical Reviews
Entry Inhibitors
maraviroc (MVC)	Selzentry®	Pfizer	Prescribing Information Microbiology Reviews Medical Reviews
Integrase Inhibitors (INIs)
raltegravir (RAL)	Isentress®	Merck	Prescribing Information Microbiology Reviews Medical Reviews
Fixed Dose Combinations
abacavir and lamivudine (ABC/3TC)	Epzicom®	Glaxo SmithKline	Prescribing Information Microbiology Reviews Medical Reviews
zidovudine and lamivudine (AZT/3TC)	Combivir®	Glaxo SmithKline	Prescribing Information Medical Reviews
abacavir, lamivudine, and zidovudine (ABC/3TC/AZT)	Trizivir®	Glaxo SmithKline	Prescribing Information Microbiology Reviews Medical Reviews
tenofovir and emtricitabine (TDF/FTC)	Truvada®	Gilead	Prescribing Information Microbiology Reviews Medical Reviews
tenofovir, emtricitabine, and efavirenz (TDF/FTC/EFV)	Atripla®	Gilead/Bristol-Myers Squibb	Prescribing Information Microbiology Reviews Medical Reviews
rilpivirine, emtricitabine and tenofovir (RPV/FTC/TDF)	Complera®	Gilead/Tibotec	Prescribing Information
Generic Fixed Dose Combinations
lamivudine and zidovudine (3TC/AZT)	Duovir	Cipla	Prescribing Information
nevirapine, lamivudine, and zidovudine (NVP/3TC/AZT)	Duovir-N	Cipla	Prescribing Information
nevirapine, lamivudine, and stavudine (NVP/3TC/D4T)	Triomune	Cipla	Prescribing Information

Educational and CME Sites

Site/URL	Description
Clinical Care Options for HIV	HIV treatment updates, conference coverage, slide sets, and tools. Registration required (free).
National AIDS Treatment Advocacy Project (NATAP)	Comprehensive coverage of publications and news on HIV treatment.
HIV and Hepatitis.com	Up to date news coverage and conference highlights.
Medscape HIV/AIDS	Extensive resource centers, journals, and news on a number of conditions. Registration required (free).
IAS-USA	International AIDS Society-USA resources, including CME course offerings, online case-based CME modules, full-text electronic versions of Topics in HIV Medicine issues, and other resources
Johns Hopkins AIDS Service	POC-IT HIV Guide. Registration required (free).
AIDS Education Global Information System (AEGIS)	Patient newsletters, physician-oriented review journals
The Body	News, conference coverage, patient education, "Ask the Experts"
Physicians Research Network	Registration required (free).
International Association of Physicians in AIDS Care (IAPAC)	Comprehensive listing for both IAPAC members and non-IAPAC conferences.
Aidsmap	Community-based organization in the UK.
Project Inform	Patient education, Hotline, Outreach programs

Biomedical Journals Publishing Clinical and Scientific HIV Studies

Journal/URL	Access Policy
AIDS	Free access to all research publications. Subscription required for full access.
AIDS Research and Human Retroviruses	Instant Online publication 72 hours after acceptance. Complimentary access to some contents, requires registration. Subscription required for full access.
AIDS Reviews	Open access to all. Most recent articles requires subscription.
Annals of Internal Medicine	Free access to full text 6 months after publication and to all original research back to 1993. Some articles can be purchased for $15.
Antimicrobial Agents and Chemotherapy	Free access to full-text articles 6 months after publication. Access to newly published articles requires a subscription. Tables of contents, abstracts, and search features are freely available.
Antiviral Therapy	Subscription needed for full access.
British Medical Journal (BMJ)	Free access to all research publication. Open access publication are deposited and available for free from PubMed Central. Newly published articles requires subscription.
Clinical Infectious Diseases	Requires subscription to access full text or to order back-issues.
HIV Clinical Trials	Subscription needed for full access.
HIV Medicine	Full text requires a subscription.
Journal of Acquired Immune Deficiency Syndromes (JAIDS)	Free access to full text 1 year after publication. Requires subscription to access newly published articles.
Journal of Clinical Microbiology	Free access to full-text articles 6 months after publication. Subscription required for full access.
Journal of Infectious Dieases	Requires subscription to access full text or to order back-issues.
Journal of the American Medical Association (JAMA)	Public access to all other JAMA & Archives Journals; Subscription needed for full access.
Journal of Virology	Free and permanent access online immediately upon publication, without subscription charges. Access to newly published articles requires subscription.
Lancet	Access to all abstracts and selected full text with free registration. Subscription needed for full access.
MMWR Reports on HIV/AIDS	Open access.
Nature	Requires personal subscription to access the content.
Nature Medicine	Requires personal subscription to access the content.
New England Journal of Medicine (NEJM)	Subscription required for full access.
Proceedings of the National Academy of Sciences (PNAS)	Open access.
Public Library of Science (PLOS) PLOS Biology PLOS Medicine *PLOS Pathogens	Open access.
Retrovirology	Open access.
Science	Limited open access. Requires subscription for full access.
Topics in HIV Medicine	Open access.

Meeting/URL	Description
Conference on Retroviruses and Opportunistic Infections (CROI)	Sponsored by the Foundation of Retroviral and Human Health, NIAID and CDC. Abstracts (1997 - 2008), Posters (1999 - 2008), and selected presentations (1999 - 2008) are online.
IAS Conferences	International AIDS Conferences in Rome Italy, 2011 and Washington DC, 2012 sponsored by the International AIDS Society (IAS).
International HIV Drug Resistance Workshop	Sponsored by Informed Horizons. See also www.informedhorizons.com for past and future conferences.
Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)	American Society for Microbiology. Site contains resources from ICAAC 2002-2012.
Infectious Diseases Society of America (IDSA)	Abstracts and videotapes can be ordered online.
International Workshop of HIV Dynamics and Evolution	Sponsored by the University of California, San Diego. Submit abstracts and register online.
HIV Drug Resistance Program Symposium: Antiviral Drug Resistance	Sponsored by the HIV Drug Resistance Program, National Cancer Institute. Abstracts available online.
European AIDS Conference	Sponsored by the European AIDS Clinical Society (EACS). Information on previous conferences can be found here.
European HIV Drug Resistance Workshop	Abstracts and presentations from 2011 and 2010 available online.
HIV Pathogenesis	Keystone Symposia.
Frontiers in Drug Development for Antiretroviral Therapies (HIV DART)	Sponsored by Informed Horizons. See also www.informedhorizons.com for past or future conferences.
Virology Education	Large number of medical workshops, conferences, and courses.
South African HIV Drug resistance and bioinformatics workshops	HIV-1 drug resistance and bioinformatics workshops organized in South Africa. It organizes the 6th South African HIV Drug Resistance and Treatment Monitoring Workshop in 2011

HIV/AIDS Research Databases and Programs

Database	Description
HIV Drug Resistance Database	Maintained at Stanford University. Annotated collection of reverse transcriptase and protease sequenceslinked to drug treatment histories and drug susceptibility test results
Los Alamos National Laboratories	Maintained by the Theoretical Biology Group at LANL. HIV Molecular Immunology Database: Contains an annotated searchable collection of HIV-1 cytotoxic and helper T-cell epitopes and antibody binding sites. HIV Sequence Database: Contains curated HIV sequence alignments, analysis research tools and technical reviews. HIV Drug Resistance Database: Compilation of drug resistance mutations Vaccine Trials Database:NIH-funded database of HIV/SIV vaccine trials in nonhuman primates.
NIAID sites	Anti-HIV Compounds: chemical structures and in vitro activity of approved and experimental compounds. AIDS Research & Reference Reagent Program: maintains and provides laboratory reserach reagents including cell lines, viruses, proteins.
NCBI Sites	HIV-1, Human Protein Interaction Database: maintained by the NCBI in collaboration with the Southern Research Institute, initiated by NIAID. Entrez PubMed: NLM bibliographic database, integrates sequence data with MEDLINE and Protein Data Bank (PDB) GenBank: contains genetic sequence data. Retrovirus resources (Hot Spots) referenced to HIV-1 and HIV-2.
HIV Structural Database	Structural database maintained at the NCI devoted to HIV and SIV protease and RT
BioAfrica (Bioinformatics for HIV Research in Africa)	Contains information on HIV proteomics, subtype C distribution, and the REGA HIV-1 subtype tool

Clinical Trials

Institution/URL	Description
AIDS Treatment Data Network	Guide for health-care personnel and patients. Information on AIDS Drug Assistance Programs (ADAP).
AIDSinfo	DHHS. Browse and search through clinical trials. Summary of completed and ongoing trials.
ClinicalTrials.gov	NIH database of ongoing clinical research trials. Search engine.
The Adult AIDS Clinical Trials Group (ACTG)	Password required for ACTG protocols, technical documents (e.g. ACTG Virology Manual), member directory. Public site; www.aactg.org
Centers for AIDS Research (CFAR)	Links to each of the CFAR sites.
Bulletin of Experimental Treatments for AIDS (BETA)	Bulletin of clinical trials and other resources.

Telephone Consultation Services

Title/URL	Description
National Clinicians' Post-Exposure Prophylaxis Hotline	24-Hour advice on managing occupational exposures to HIV, hepatitis, and other blood borne pathogens. "PEPline" (888-HIV-4911)
National HIV Telephone Consultation Service	Case consultation for physicians, nurses, and other health-care givers. "Warmline" (800-933-3413)
National Perinatal HIV Consultation and Referral Service	24-Hour advice on treating infected pregnant women and infants (888-448-8765)

HIV Treatment Websites

Database

Resources

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